Sentence examples for alignment to genome from inspiring English sources
Additionally, in a preliminary alignment to genome, overlapping reads were aggregated together into contiguous intervals.
For the genome alignment module, the existing tools for EST to genome alignment do not provide customizable clustering function.
Many algorithms have been introduced to reconstruct gene structures from spliced alignments of transcripts to genome sequences [ 6- 9].
An efficient algorithm for the nucleotide-level transcriptome to genome alignment with structural alterations problem.
This allows the exact transcript to genome alignment without structural alterations to be performed in O NM) time.
Below we describe a nucleotide-level transcriptome to genome alignment formulation for detection of structural alterations within the transcript.
The first stage examines contig alignments to genomic sequences (contig-to-genome alignments) and identifies anomalous or non-reference (candidate) contigs that have a variety of alignment topologies.
TopHat performs an alignment to the genome by dividing the cDNA sequence, and when it matches the genome, TopHat presumes that place to be a splice junction.
A "uniquely aligned" read is defined as a read with a max scoring alignment to the genome scoring (1) at least 24 and (2) at least four higher than any of the other alignments of that read to the genome.
Homology determined by alignment to each genome with reciprocal alignment by BLASTP.
State 2 is cessation of alignment to the genome.
