Although the HMM framework can cover entire genomic regions by scanning alignments with small windows, the MCMC framework developed by Rannala and Yang uses a fraction of whole-genome alignments to avoid the effect of recombination.
The program calculates the correlation between two matrices shifting positions; the correlation is normalized based on the width of the alignment to avoid high correlation based on few flanking positions.
The program calculates the correlation between two matrices shifting positions; the correlation is normalized based on the width of the alignment to avoid high correlation based on few flanking positions (Supplementary file 1).
Although D. papillatum appeared to be relatively fast-evolving (fig. 1), we kept this taxon in the alignment to avoid leaving E. gracilis as a single, unpaired long branch of Euglenozoa within the Discoba clade.
(6) proposed AlleleSeq for constructing a modified diploid genome by inserting SNPs and indels into the reference genome and using this diploid genome as the reference during alignment to avoid errors caused by reference bias.
Several algorithms have been derived previously to annotate CB regions, with the primary goal of 'masking' such regions before sequence alignment, to avoid incorrect inference of homology [e.g. SEG, (16); and CAST (17)].
Your sleep style plays a big role in the type of pillow you'll need, since the pillow should ideally fill the gap between your head and shoulders when you lie down, keeping your head in perfect alignment to avoid neck pain.
Many assemblers are designed to tolerate imperfect sequence alignment to avoid missing true joins.
We encouraged the players to concentrate on the quality of their movements and put emphasis on core stability, hip control, and proper knee alignment to avoid excessive knee valgus during both static and dynamic movements (fig 2).
