The phrase "alignment strategy in" is correct and usable in written English.
It can be used when discussing a specific approach or plan related to alignment within a particular context, such as business, technology, or project management.
Example: "The alignment strategy in our organization focuses on ensuring that all departments work towards common goals."
Alternatives: "alignment approach in" or "alignment plan in".
Many commonly-used multiple sequence alignment programs use the progressive sequence alignment strategy in which the alignment and the locations of insertions and deletions are permanently fixed in the growing alignment [21].
For comparison purposes, we also applied this alignment strategy in the TopHat and MapSplice pipelines.
Although the first aim of the feedback session was to add information to the collected data from interviews and document analysis, we experienced that such a feedback session is an alignment strategy in itself.
Alignment to individualized transcriptomes improves eQTL call accuracy for all gene biotypes that exhibit eQTL differences from alignment strategy in the simulation; pseudogenes in particular are sensitive to false positive distant eQTL when aligned to the reference transcriptome (see explanation below).
Despite the great potential of the embedded alignment strategies in answering a diverse set of biological questions, their computational costs are prohibitively expensive, a problem that arises out of the current method of generating and analyzing embedded sequences.
Abundance estimates for 124 genes (124 of 714 genes) differ by >10% between alignment strategies in the real data and show an improvement from alignment to NCBIM37 in the simulation study (red circles in Figure 3C).
Moreover, this suggests that the simulation study underestimated the actual differences in gene-level abundance estimates between alignment strategies, at least for the set of 2984 genes whose abundance estimates differ by >10% between alignment strategies in the real liver data.
HPG-Methyl implements the alignment strategy described in Section 2. However, in order to take advantage of the parallel architectures available in current computers, it follows a very similar parallel pipeline to the one used by HPG-Aligner (Martínez et al., 2013; Tárraga et al., 2014), but adapted to the specific features of methylation analysis.
Sequences with no known 3D structure were initially aligned by (i) identifying the most conserved segments in the PSI-BLAST HSP alignments with the Ballast [55] program and (ii) using these conserved segments as anchors for the progressive multiple alignment strategy implemented in DbClustal [56].
A schematic diagram of the alignment strategy used in this study.
This is probably due to the global alignment strategy used in AVID, which assumes that the order of the functionally conserved regions has been preserved [ 20].
