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The computational efficiency of this step is a deciding factor in design of alignment strategies for large sets of noisy data and in development of three-dimensional structure refinement methods.
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The alignment strategy for the PT consists of two parts: the hardware measurement by theodolite and the software alignment using long muon tracks.
Here, an easy alignment strategy for multi-level micropatterning is proposed enabling the broadening of patterning possibilities and the increase of architecturing complexity.
This alignment strategy for finding drug targets is reasonable.
We have shown that the position of Exhippolysmata depends on the alignment strategy for 16S and the taxon sampling.
We also explored an alternative, spliced alignment strategy for finding TICs by identifying splicing events within individual reads using our GSNAP program [ 27].
We find that RNA-Seq allelic ratios from standard alignment methods correlate poorly with SNaPshot, but applying alternative alignment strategies and correcting for observed biases significantly improves correlations.
Moreover, this suggests that the simulation study underestimated the actual differences in gene-level abundance estimates between alignment strategies, at least for the set of 2984 genes whose abundance estimates differ by >10% between alignment strategies in the real liver data.
This illustrates the need for more alignment strategies based on the Blurring the Boundaries model.
For the polymorphism and evolutionary analyses, different alignment strategies were conducted.
Four alignment strategies used Clustal W [48] and SATé [21], and MrBayes [49] were applied in this study: the whole-ITS Clustal W. Clustal W is used for multiple alignment and MrBayes is used for phylogenetic inference.
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