Exact(5)
Tom Brady was a master at diagnosing and, with the occasional alignment shift, creating those mismatches before the snap.
This band alignment shift would influence the leakage current density-electrical field (J-E) characteristics of the samples (Figure 6).
In addition, according to the thermal vacuum test performed before launch, it is expected that the mutual alignment shift may at worst be as large as 0.5 mrad (=0.03°).
When sequence reads were mapped back to mature miRNAs, the alignment shift may result in mismatches.
Two transmembrane helices contain an alignment shift of three residues, resulting in a clear local increase of the QMEANBrane scores of the model built with the HHBlits alignment relative to the model built with the BLAST alignment.
Similar(53)
In 2000, the portion of US 202 between I-95 and DE 141 (Powder Mill Road) was improved, with the alignment shifted to eliminate a few curves, the intersections at DE 261 and DE 141 improved, and a southbound transit lane added.
Those structures requiring very large alignment shifts, or having poor correlation with the remainder of the data set, were removed.
Models based on different target-template alignments have been compared to test QMEANBrane's capability of detecting incorrect alignments, particularly alignment shifts in transmembrane helices.
Conversely, valgus limb alignment shifts the center of pressure laterally and reduces the external adduction moment about the knee during gait, which increases lateral-compartment loading (e.g., lateral condyles).
The low number of pairwise atomic interactions in combination with the regular hydrophobicity pattern often observed in alignment shifts by two residues hamper the reliable detection of such errors and require further investigation.
For estimating the effect of alignment shifts in models with otherwise correct fold and stereochemistry, we created pseudomodels starting from the original protein structure and introducing threading errors of increasing magnitude for different representative structure architectures from CATH (Cuff et al., 2011).
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