Organizations like the Bill and Melinda Gates Foundation and Genentech have built governance, infrastructure and measurement systems to ensure alignment, serving to reinforce the right behaviors over time.
The alignments served to make a consensus for every allele, and are provided as Additional Files 2, 3, 4, 5, 6, 7, 8, 9.
Nevertheless, stepwise approaches with manual curation of LRIM protein sequence alignments served to identify characteristic features that define the family and help to infer likely sequence-structure-function relationships.
These genome alignments also served to visualize and quantify the overall quality of the individual draft assemblies for the test strains.
These results suggest that the experimentally observed active remodeling of ECM fibers by fibroblasts under interstitial flow to a perpendicular alignment could serve to decrease the shear and drag forces on the cell.
This served to increase alignment quality, a possible source of false positive positive selection.
The multiple alignment of the retrieved sequences served to reconstruct a neighbor-joining phylogeny of Arr and closely related enzymes.
SIM, an alignment tool for analysis of local similarity in nucleotide and amino-acid sequences (http://web.expasy.org/sim/) [Huang and Miller, 1991], served to generate pairwise alignments of sacsin versus internal repeats using default parameters.
The route proceeds west along the former alignment of Highway 17, which it has served to replace.
This alignment served as input for HMMaccel, which was used to iteratively search the above mentioned plant databases with a combination of PSI-BLAST and HMMer to detect further homologs.
