The phrase "alignment sensitivity" is correct and usable in written English.
It can be used in contexts related to precision, accuracy, or the importance of alignment in various fields such as engineering, design, or psychology.
Example: "The alignment sensitivity of the instrument is crucial for obtaining accurate measurements."
Alternatives: "alignment precision" or "alignment responsiveness".
In terms of alignment sensitivity, SSEARCH with sensitive matrices is better than BLAST-based methods, partly because the BLAST algorithm including CS-BLAST, and also SSEARCH with MIQS.SCOP40-v, tends to generate shorter alignment (Supplementary Fig. S4).
For mapped read counts, not only we considered uniquely mapped reads but also multimapped reads were included in the mapped reads to provide a rough perspective of alignment sensitivity for each aligner.
The alignment sensitivity, the ratio of correctly aligned residue pairs to structurally equivalent residue pairs, is defined as (N∩S /S, where N is the number of residue pairs in the sequence alignment and S is the number of ones in the reference alignment.
For both datasets, HIA is significantly faster than all of the other aligners except BWA MEM and SOAP2 while retaining good alignment sensitivity and precision.
We tested alignment sensitivity by repeating phylogenetic analyses on a data set in which ambiguously aligned regions were removed by excluding positions in each direction until we came to nucleotides that were invariant in all taxa in the analysis [ 68].
Transmission gratings offer low alignment sensitivity, which helps minimize alignment errors.
As shown in Figure 3B, experimental conditions produced significantly different alignment sensitivities [within-subjects one-way ANOVA: F 2, 20) = 14.54, p<.0001].
We conducted follow-up comparisons for alignment sensitivities; all comparisons were two-tailed paired samples t-tests, and all significance values were compared to a Bonferroni-corrected alpha level for four comparisons (p<0.0125).
Considering a probability-weighted distribution of alignments removes sensitivity to alignment errors, properly accommodates regions of alignment uncertainty, and increases the accuracy of functional element prediction.
Particles of known fluorescent characteristics (Calbrite particles; BD Biosciences) were utilized to examine instrument alignment and sensitivity.
Table 7 shows the execution times, (measured in minutes) required to provide the alignments whose sensitivity is shown in Table 6.
