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Van Houten (1983) and Ngounouno et al. (2000) interpreted the CVL as a volcanic and subvolcanic alignment resulting from hotspot activity.
Wasabi permits the user to see the sequence alignment resulting from phylogenetic placement comparing how cluster centroids match the closest reference sequence.
When the subnetwork alignment resulting from the initial seed is terminated, the next best unaligned pair is chosen as a new seed.
The result at this stage is a sequence alignment (resulting from the Matt structural alignment) with conserved beta-strand pairs annotated according to the residue positions and conformation (buried or exposed to solvent).
In a population study of 2,644 knees, both valgus and varus alignment, resulting from genetic, developmental, and traumatic factors, were found to be highly associated with the development of OA [ 80].
In order to compare our results with the results from these studies, we show the accuracy,, the remaining number of nucleotides after the gaps are removed from the alignment, and the total length of the alignment resulting from the introduction of indels during the evolution of the sequences, all plotted as a function of G/S.
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ESTScan was used to decide the sequence direction and to predict coding regions of a unigene if no alignment resulted from the above databases [ 65].
The loss of normal disc height or lordotic alignment resulted from disc herniation or degeneration was documented to induce pathologic changes in the spinal kinematics and may accelerate degeneration of the functional motion unit of spine [ 23].
The alignments resulting from the BLAST program were then subjected to QRNA analysis [ 5].
We used the alignments resulting from the quality control steps to produce pileup files using samtools [ 48], from which we called SNPs using a custom algorithm.
Possible PCR-mediated recombination errors as well as homopolymer run-associated sequencing errors were picked up manually by checking the pairwise alignments resulting from the FASTA search.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com