Sentence examples for alignment rather than the from inspiring English sources

Where point mutations were introduced into a GPCR, the mutant residue type was used in the sequence alignment rather than the wild-type residue.

In contrast to thermodynamic methods, which explicitly model RNA structures including loop length and base-stacking effects, phylo-grammar-based gene models primarily score candidate structured sequence based on the statistical evolutionary signal that the structure leaves in the multiple alignment, rather than the energetics of the structure itself.

This method should be less sensitive than targeted alignment, because the version of GSNAP we used requires 14 nt on each side of an exon-exon junction to identify a spliced alignment, rather than the 8 nt we used for targeted alignment.

Together, these data show that loss of Sall2 causes coloboma in mice as well as humans, and suggests that Sall2 is required for correct growth of the optic fissure margins towards each other and their alignment, rather than the process of dissolving the basement membrane.

Thus, one can trace the level of accuracy of phylogenetic reconstruction based on the percentage of gaps in the alignment rather than on the rates of substitution or indel introduction.

From the figure legend, it appears that the full length proteins were used for the alignment (rather than just the conserved domain).

Indeed, we rely on structural alignments which are generally safer than sequence alignments, we use pairwise alignments rather than the more difficult multiple structure alignments, and we focus on comparisons between individual domains within superfamilies.

Due to the relatively low degree of sequence conservation at the nucleotide level within some of these families, phylogenetic inference was carried out on amino acid alignment, rather than attempting alignment at the nucleotide level.

By running and passing out of the alignment rather than kicking, Piedmont makes defensive coordinators woozy; when the offensive linemen look like Jerry Rice, it's pretty tough to tell who's going out for a pass.

Here, since a multiple sequence alignment rather than a single sequence exists, the arithmetic mean of each codon position was calculated.

This included applying stringent spatial smoothing (with a 12 mm full-width at half-maximum Gaussian; Supplementary Fig. 4) to overcome intersubject variability, and aligning the data using cortex-based surface alignment rather than volume alignment (Supplementary Fig. 5).