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For CoMFA calculations, three different fitting methods for alignment process were investigated.
Most of the parameters in the alignment process were set to their default values.
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The whole alignment process is verified by calculating the RMSD between aligned and nearest template coordinates.
Once a change in reference DNA is requested (at the additional alignment options page [ 8]), the alignment process is automatically reinitiated using the highest scoring aligning region of the selected genome as the new input reference DNA. Figure 5 highlights the genome-specific variability of less-conserved sequences between vertebrate MCS regions.
This is a protein-coding region so the alignment process is not difficult.
Then, the reconstruction alignment process is iterated until the final matched neurites are smoothly stitched (Supplement, Section 2.4).
The number of particles of the particle filter used in the alignment process was set to 250.
Our alignment process is partly motivated by advances in cognitive psychology of human perception (see, e.g., [25]).
The alignment process is achieved by computing the real-time relative motion between the different inertial units.
This alignment process is particularly suitable since a target pressure distribution is specified in the inverse design problem.
A theoretical model describing the alignment process is presented and used to quantify the effects of key parameters on the time needed for the alignment process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com