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Electron-beam lithography process controlled the alignment, position, and location of NRAs.
For this data set we then calculate the mutual information between each alignment position and each molecular descriptor.
The probability of occurrence of each amino acid is read from the HMM profiles, for each alignment position and for both the subfamilies [29].
We selected the particular subsets for agonists, antagonists and the G-Protein coupling from the entire data set of 1664 ligand-receptor pairs and calculated the mutual information between each alignment position and each molecular descriptor.
It scans each alignment position and employs a scoring scheme, tested on diverse datasets, to detect structurally conserved regions observed in all domain superfamily members and distinguishes such regions from indel regions where differences between members in terms of length or structural type accumulate.
Mean Dayhoff PAM250 log scores were calculated for each alignment position and grouped by domain.
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Topographic conditions, especially the average natural ground slopes, exert a tremendous influence on alignment positions and methods for railway location.
Correlation analysis of Slig values to amino acid sequence similarity scores – obtained via multiple sequence alignments – was performed for individual residue alignment positions and sets of residues on 13 DHFRs.
Highly variable gene fragments, with gappy alignments, can lose a significant amount of phylogenetic information when filtered out of ambiguous alignment positions, and consequently contribute with unreliable calibrations.
**The start and stop positions of the ribosomal RNAs were predicted based on conserved multiple alignment positions and the borders with neighboring genes.
In the present study, we investigated poor and conflicting resolutions in these clades using highly variable alignment positions and long-branches as proxies for phylogenetic noise.
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