Sentence examples for alignment particularly from inspiring English sources

Increasing allowed alignment mismatches helps overcome missing genotypes, inaccuracies in the reference genome, and errors in the sequence reads, but also results in increased erroneous sequence alignment, particularly when aligning shorter reads.

After an individual's genetic variation is included in the alignment, particularly in the parent gene, many of these reads will align uniquely to the parent gene and be weighted accordingly by the EM algorithm.

A significant challenge in fusion is achieving both spatial and temporal alignment, particularly in pulmonary and cardiac systems [9].

This tubular configuration facilitates simple packaging with the precise optical alignment, particularly for forward-viewing endomicroscopic applications.

The significant disposal of angular momentum in the product orbital motion, l → j' + l' declines the product rotational alignment, particularly at lower collision energies, so the calculated P2 values deviate slightly from -0.5, which could also be supported by the P(θ r ) results.

The short length of sequence reads, e.g. 50 base pairs, can pose considerable challenges in achieving accurate genome alignment, particularly if the genome sequence is highly polymorphic.

After assembly, the intron/exon junctions were visually inspected and adjusted to ensure proper alignments, particularly for intron splice sites, as software frequently fails to align the A-Trich sequences properly.

We have shown that the partitioning of the alignment into well characterised blocks allows a judicious combination of complementary methods resulting in more accurate alignments, particularly in the less well conserved regions.

Models based on different target-template alignments have been compared to test QMEANBrane's capability of detecting incorrect alignments, particularly alignment shifts in transmembrane helices.

The scant sequence homology and size polymorphism of these degenerated retroposons make for irresolute multiple alignments, particularly with regards to the very heterogeneous SIDER1 subgroup.

On the other hand, some true functional paralogs may be missing from the alignments, particularly those resulting from ancient duplications, due to homology below the threshold used by the reciprocal BLAST algorithm (see Methods).