Suggestions(1)
Exact(6)
However, if we optimize the alignment only for the principal subspace, we might walk further away in the orthogonal complement, ignoring details not included in our model but which indeed might be important for the registration.
[12] have recently presented a methodology for de novo ncRNA annotation which relies on an input multiple alignment only for homology detection, and so is capable of detecting conserved structure even in the presence of local mis-alignment.
We perform pairwise alignment only for the remaining networks.
However, we confirmed this alignment only for regions around TSSs derived from broad promoters, not for those around TSSs derived from peak promoters.
Although our anchor points enforced the correct alignment only for a single column, most parts of the core blocks were correctly aligned as shown in Figure 4.
Because of the high sequence divergence of the Pol ε C-terminal domain, we were able to construct a reliable alignment only for approximately 280 amino acid residues from the Exo and Pol domains of B-family DdDps.
Similar(54)
*The V-J rearrangement observed in the pre-B ALL is likely to be normal V-D-J, however we obtained full read alignments only for read pairs mapping one end to IGHJ4 and the other to IGHV4-34.
Alignment only possible for small area (from mm2 to cm2).
Since the entire sequence of the domain was required for a good alignment, only 26 sequences for which the complete sequence was available were used.
For peak alignment, only the (recommended) option of the "fast aligner" was tested as the other alignment procedure resulted in frequent crashes of the computer.
Alignments were inspected by eye and for each alignment only protein sequences showing no misalignment and having a minimum ORF length (CYPs: 450 nt, CCEs: 450 nt, GSTs: 300 nt, UGTs: 450 nt) were retained for the final alignment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com