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The curve alignment on the basis of the detected events allows to find the unfolding pathways for bR.
Bayesian inference was performed by partitioning the concatenate alignment on the basis of individual loci using a GTR+Γ+I model.
To resolve regions for which there is a lack of agreement, we generated model B by manually adjusting the alignment on the basis of the results of model A as evaluated by HDX.
An exception to this was the alignment of tRNA genes, for which Yamanoue et al. [ 27] modified the alignment on the basis of the secondary structure, estimated with DNASIS.
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Different evolutionary models were used to calculate the likelihood and pSH values for the maxgen and maxspe alignments on the basis of aa, 12cdp and 123cdp nt sequences (Table 4).
We created the nucleotide sequence alignments on the basis of amino acid alignments and calculated the nucleotide replacements in the form of 4 × 4 NRM, individually for three codon positions for three different groups of orthologs under study.
Among other advantages, molecular morphometrics makes it possible to identify characters informative about parsimony that are not found in the primary sequence [ 16, 17], and to correct primary alignments on the basis of secondary structure information [ 3].
Safety Criteria allow to express a judgment on road alignment homogeneity on the basis of the comparison between design speed SD and operating speed S85 along the alignments (operating speed is represented by the 85th-percentile speed of a sample of vehicles).
Nucleotide sequences were then aligned, on the basis of protein alignment, with the Tranalign program of the EMBOSS package.
We then scaled the CRE across the two families with the conservation in DHA1 which helped us to enlist the alignment positions on the basis of high CRE as well as high conservation across the entire DHA1 family.
To select the alignment positions on the basis of both, high conservation across DHA1 and high CREi, the normalized CREi was further scaled with respect to the RENULL as given by Equation 2. This was referred to as CRES and represented as per the following equation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com