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It is shown that the interaction between such a simplified numerical treatment of the viscous terms and the alignment of the cell interfaces with the coordinate system can result in an erroneous (non-physical) calculation of the pressure field.
Interestingly, these extensions do not appear to strongly influence the overall alignment of the cell with the topographical pattern.
In the Magnetospirilla, the 'compass needle' is set parallel to the cell's direction of movement, allowing passive alignment of the cell along geomagnetic field lines [5].
(We define the alignment of the cell as the alignment of the ellipse that best fits the cell shape).
First, we examined both the cell velocity and the alignment of the cell shape as a function of angle with respect to the nanoridges.
We fabricated gratings with nanoridge spacings of 0.4, 0.6, 0.8, 1.0, 1.5, 1.5, 2, 3, 5, and 10 μm. Figure 2 A shows the distributions of the alignment of the cell long axis with respect to the ridge direction (weighted by eccentricity) for several of these gratings.
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These composite substrates appear to show a useful degree of alignment of the cells.
Excellent alignment of the cells is induced by fabrication of 25 μm wide microchannels in these sheets.
Alignment of the cells was characterized according to their elongation and orientation using the fast Fourier transform data and binary image analysis.
Alignment of the cells was characterized by elongation of the cell shape and orientation of the α-actin filaments supported by the FFT data.
Earlier hypotheses have assumed that gravitactic orientation in flagellates, such as the photosynthetic unicell Euglena gracilis, is brought about by passive alignment of the cells in the water column by being tail heavy.
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