The phrase "alignment of reads" is correct and usable in written English.
It is typically used in the context of bioinformatics or genomics, referring to the process of arranging DNA or RNA sequences for analysis.
Example: "The alignment of reads is crucial for accurate variant calling in genomic studies."
Alternatives: "sequencing alignment" or "read alignment".
For HPV type detection, we indexed the multi-fasta HPV reference file using BWA aligner followed by alignment of reads to indexed genome (Li and Durbin, 2009).
MapNext first conducts the unspliced alignment of all query reads, then conducts the spliced alignment of reads that cannot be aligned at the first stage.
Alignment of reads to the genome scaffolds indicate 57% of the sequence reads aligned to L. bicolor or aspen genomic sequence.
Alignment of reads against reference genome HG19 was performed using TopHat and analyzed using Cufflinks.
(a) Illustration of the HCV genome with sequencing read coverage frequency (black contour) and alignment of reads (grey bars), data merged from reads of three isolates.
Long terminal repeats (LTRs) were delimited according to excessively increased coverage at the left end of the genomes due to the alignment of reads of both the LTRs.
The sequences were refined in an iterative process of alignment of reads using bowtie2 v2.2.330, pileup using samtools v0.1.19-44428cd31 and creating a new reference sequence using FastaAlternateReferenceMaker-GATK v3.3-0-g37228af32.
The alignment of reads was used to build consensus genome sequences for 7302R.
Thus, the primary value of a reference genome sequence is that it greatly facilitates and accelerates phenotype sequencing, by enabling rapid alignment of reads and detection of mutations.
Specifically, all software used previously allowed random alignment of reads having multiple matches, thus creating noise in the detection of the variant in nearly-identical repeats.
Contigs and singletons obtained from alignment of reads in each cluster imply putative gene sequences, which were analyzed for homology searches in existing sequence databases and open reading frame (ORF) discovery.
