Sentence examples for alignment of probes from inspiring English sources
Although this may seem inconsistent, further examination of the alignment of probes to gene revealed that different probesets for Tsn aligned to different populations of alternatively polyadenylated transcripts.
The alignment of probes to Ensembl transcripts gave 95,008 transcript-specific and 180,403 gene-specific probes out of a total of 247,965 probes (Table 1, supporting tables S1 and S2, and dataset S1).
PanCGHweb performs the following steps: (i) orthology grouping; (ii) alignment of probes to genes; and (iii) genotype calling.
Additionally, the following tab-delimited files can be downloaded: OGs list, alignment of probes to genes, presence/absence of OGs and presence score of OGs.
Currently available conversion methods rely on manufacturer annotations, which are often incomplete, or on direct alignment of probes from different platforms, which often fail to yield acceptable genewise correlation.
In the present study alignment of probe sequences of the Affymetrix microarray HG-U133A with Ensembl transcript sequences was performed to define transcript-specific probe sets.
One of the powers of this approach is that the entire pipeline of methods used to assemble the correlation matrix is completely metadata independent – only the genomic alignment of probe sequences and the quantitative measurements made by the microarray were used.
Chromosome 3 alignment of probe sets (represented genes) was determined based on the UCSC Human Genome Browser database, where 535 probe sets mapped to genes on the chromosome 3p arm and 612 probe sets mapped to genes on the chromosome 3q arm.
However, due to cross-alignment of probes, we cannot unequivocally assign cDNAs from the duplicate copies to a specific locus.
Dai et al. [5] introduced re-defined probe sets after re-alignments of probe sequences to genes as well as transcripts.
The algorithm consists of four steps: 1. Exact alignments of probe sequences to the genome are found using a hash table.
