Sentence examples for alignment of chromosomes from inspiring English sources

The nuclear survivin is active in the regulation of mitosis and contributes as a chromosomal passenger complex protein to the proper alignment of chromosomes, chromatin-associated spindle formation and kinetochore microtubule attachment [ 34].

These results demonstrate that CRMP4 plays an important role in the proper alignment of chromosomes during mitosis.

An additional checkpoint, the spindle assembly checkpoint, monitors the proper alignment of chromosomes during mitosis and can be activated by anti-mitotic drugs such as paclitaxel.

It contributes to microtubule instability and is necessary for both the correct alignment of chromosomes on mitotic spindles and biorientation (the capture of sister kinetochores by microtubules from opposite spindle poles) prior to anaphase [13].

It is necessary for formation of mitotic spindles, separation of the centrosomes after the mitotic spindle has been formed and ensures correct organization and alignment of chromosomes during prometaphase [78], [79].

These results indicate that MFAP1 is required for the alignment of chromosomes at the metaphase plate.

Finally, about 10% of the cells that were engaged in centromere coupling (CEN1's associated with separate Mtw1 foci) exhibited linear SC (Fig. 2) demonstrating that, in some cells, considerable synapsis occurs before the homologous CEN1's become aligned - consistent with the model that the alignment of chromosome arms generally precedes the alignment of homologous centromeres.

Alignment of chromosome-derived reads with contigs was used to assign contigs to chromosomes and to correct assembly errors.

In all, alignment of chromosome cores and their agglomeration at the bouquet base seems to facilitate synapsis initiation between previously distant homologous chromosomes.

18 The "Compare Regions" resource provided by Seed allows alignment of chromosome loci that contain open reading frames for homologous proteins, or, in other words, to pin these loci through genes that are homologous to a query sequence.

The probability by which each alignment column is produced by the different genealogies in the model is readily computed by posterior decoding of the fitted HMM. Figure 2B shows the probability of each genealogy along 3kb of a genomic alignment of chromosome 2 from human, chimpanzee, and gorilla.