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To determine the role of the alignment method in generating strand bias, we aligned our samples using an additional aligner: Bowtie [ 13].
Each query sequence was aligned separately with each of the training profiles using the sequence to profile alignment method in ClustalW 28 and checked for the conservation of cysteines.
Therefore, we just identified orthologs for all genes using RBH-based pairwise alignment method in PlantOrDB.
The sequence alignment method in the proposed algorithm was performed using BLASTP [ 21].
The subset of genes most sensitive to alignment method in real data consists primarily of closely related gene families and protein-coding genes with retrotransposed pseudogenes.
We developed an efficient computational procedure for integrating two PINs with reference to the global protein network alignment method in an attempt to obtain the integrated PIN [ 42].
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Additionally, the increasing number of sequences in the biological databases is perceived as one of the upcoming challenges for alignment methods in the nearest future.
The philosophy of AGEP is analogous to the sequence alignment methods in the analysis and comparison of newly sequenced DNA.
Sbalanced scores for the common domain pairs, averaged over domain families, were 0.026 0.032 lower according to the different alignment methods in VAST alignments than the corresponding guide alignments and 0.032 0.047 lower in SABmark alignments than the corresponding guide alignments.
These proteins are subjected to rigorous and computationally expensive structure alignment methods in the second step, which is known as a match step.
We found a good agreement between the two alignment methods in the seven experiments where both blood vessels and electroporated neurons were used.
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