Sentence examples for alignment is reliable from inspiring English sources

Before the use of DIVERGE, our sequence dataset was examined to satisfy the conditions recommended by Gu et Vander Velden (2002), which permit us to obtain higher efficiency of detecting functional divergence-related residues: 1) each cluster has more than four amino acid sequences; (2) all pairwise sequence identities are <90%; and (3) multiple alignment is reliable.

The number of suboptimal hits may help to decide which alignments are reliable.

Structural modeling of proteins by homologous sequence comparison and alignment is relatively reliable.

In contrast to the peptide alignment, the SH3 domain alignment is highly reliable, mainly the alignment of n-SRC-loop and RT-loop in SH3 domains.

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This alignment is essential for reliable synaptic transmission [33] and can be regulated by diverse signaling pathways [40], [41], [42].

Accurate sequence alignment is pivotal in reliable assessment of potential mutations however selection of appropriate alignment tools is a non-trivial task complicated by the availability of multiple solutions each with its own performance characteristics.

Assuming a reliable alignment is available, phylogenetic tree topologies inferred from molecular data usually are regarded to be informative, if support for clades as estimated with bootstrapping or jackknifing methods or with Bayesian approaches is high and if at the same time a systematic bias can be excluded [e.g. [ 1- 12]].