Suggestions(1)
Exact(4)
The identification of characteristic amino acid residues in the homeodomain region (a region where the alignment is generally not ambiguous; see for instance [6]) is also considered as an alternative/complementary gene identification approach.
While we argue that coming to a final conclusion based on a pairwise BLAST alignment is generally not supportable, visualization of sequence similarity networks provides using even such a simple metric as BLAST an environment for exploring complex protein data sets and the straightforward generation of hypotheses to be tested using more rigorous methods.
Therefore, spliced alignment is generally effective only for reads having exon-exon junctions in their middle regions, away from the 14-20 nt margins at their ends.
The alignment is generally marked out on the ground by a line marked by stakes and slashed to a width of 2 meters, but sometimes it is shown by a clearing 10 meters wide, which is intended to guide the tractor operator.
Similar(56)
Although all the three methods perform well on Dataset-3 (Figure 1) because the PFMs derived from the same motif alignment are generally very similar to each other, our KFV method clearly outperforms both STAMP and MoSta.
Alignment was generally straightforward, given the overall conservation of the protein sequences.
The conserved positions in all sequences in an alignment are generally important for the stability, folding or function of the protein domain.
While our approach of constructing a global statistical model from paired sequence alignments is generally applicable to any taxa, the current study focuses on prokaryotes and mitochondria.
Accuracy of sequence alignments is generally assessed on the basis of residue pairings, but only recently developed distance measures that also include similarities in terms of gap placement have been developed (Blackburne and Whelan, 2012).
The new alignments were generally built as planned, except at Little Falls, where a bypass was to be built for Route 12.
To maintain accuracy, these alignments are generally discarded.
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