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The ROC curve for the phastCons predictions is displayed alongside the BigFoot ROC curves in Figure 3. Comparing the AUC values demonstrates how the increase in predictive accuracy caused by adding more sequence data is less than the corresponding increase caused by analyzing a distribution of alignments instead of a single alignment.
Note that for the local feature extraction, we just rotate the faces into an upright position for alignment instead of applying a projective transform to prevent unnatural distortion of local regions and then resize the facial image to 64 × 64 pixels.
Rash, for instance, could easily be modified to find a sequence of local transformations for an alignment, instead of trying to find a single rigid transformation (although a new training for Rash would be needed).
After the alignment, instead of simply parsing a BLAST output, taxonomy is assigned using a predefined taxonomy map in which a reference sequence is related to the corresponding taxonomy.
We concatenated sequences only after the alignment instead of before aligning them to avoid falsely aligning sequences from different domains.
To improve the quality of the alignments we used multiple sequence alignment instead of pairwise alignment, aligning the sequences in 21,969 groups of 40 sequences.
You will even look where your ideas intersect with an opposing approach to create alignment instead of competition.
We expect that tools for rapid application development will be further improved and will play an increasingly important role to establish responsive IT-infrastructures where the application developer can concentrate on business process alignment instead of coding and debugging.
In Japan, the conflicting environment has fostered close Japan-U.S. alignment instead of encouraging Asian reconciliation.
However, in the view of their band structures, type I band alignment instead of type II is generally achieved in these heterojunctions.
Because of computational restrictions, we used only one directional alignment instead of averaging over both directions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com