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Wound treatment with C15, however, resulted in collagen deposition with a more random collagen fiber orientation closer to unwounded dermal collagen organization, which equated to reduced alignment in comparison to that of vehicle-treated wounded skin (C15: 0.71 ± 0.02; Figures 4A 4C).
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To assess the efficacy of eBLAT alignments in comparison to the original BLAT, we compared the pairwise alignment scores (the total number of aligning bases in the input DNA) of eBLAT to those obtained with BLAT, using 10 different intergenic regions from the Drosophila melanogaster genome.
Combined with the RCS and FCS scores, this method can achieve significantly lower alignment errors in comparison to an exhaustive sampling method.
This approach drastically reduces the number of alignments computed in comparison to more general, global alignment searches [ 10], as will be shown later in the " Results and discussion" section.
Thus, it is inaccurate to assess NetDis, an alignment-free approach, in comparison to an alignment-based approach, due to the difference in the goals of the two approach categories.
In the latter case sarcomere alignment was reduced in comparison to the former.
In this paper, we simulated both hop count as well as link metric for 1500 bytes (with respect to our network model which is in alignment with MTM [23]) in comparison to our proposed metric (e.g., packet function/size) over Dijkstra as well as extended version of Dijkstra algorithm.
However, this EST still has the highest percentage alignment with NCX1 genes in comparison to the other three paralogs from other species.
We have also shown both for a vertebrate snoRNA and for four bacterial sRNAs that the addition of evolutionary information from multiple sequence alignments improves the performance in comparison to methods based on single sequences.
In particular, we tried to determine the application threshold for the global algorithm, i.e. the values of the above-mentioned parameters, which provided for the same or better quality of alignments by using the global algorithm in comparison to the quality of alignments by using the local algorithm (see the definition of the alignment quality in section 2.3).
Both programs quantify standard characteristics as well as support cell recruitment and microvascular network alignment, and were highly accurate in comparison to manual measurements for engineered tissues containing self-assembled microvessels.
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