The phrase "alignment in combination" is correct and usable in written English.
It can be used when discussing how different elements or factors work together in a coordinated manner.
Example: "The alignment in combination of various strategies led to the project's success."
Alternatives: "synchronization together" or "cohesion in conjunction".
Globally optimal sequence alignments in combination with assessment of the significance of the alignment scores resulted in striking patterns of relatedness.
This observation suggests that the failure to detect these SNVs in the HaloPlex data is not caused by allelic dropout during HaloPlex enrichment, but rather by sequencing errors or alignment artifacts in combination with low coverage leading to false positive SNV calls in the WGS data.
To detect conserved motifs related to regulation of gene expression lying upstream or downstream of the MT genes, the multiple sequence alignment programs MEME and Gibbs Sampler were used [76] [77], as well as alignment in pairwise combinations using the BLAST 2 sequences webpage at NCBI.
The EST and protein libraries input to MAKER2 for sequence alignments are used in combination with gene predictions to produce annotations, and would ideally be from the organism being annotated (e.g., from a previous transcriptome sequencing project).
The modules, well illuminated by cosmic ray particles, were aligned using two track-based alignment algorithms in sequence in combination with survey measurements.
The editing and alignment were done manually in combination with ClustalX software Version 2.0.9 [ 69].
In brief, the SAS75 stereotaxic alignment system was used in combination with the EM70G manipulator (Kopf Instruments).
Data analysis was performed using state-of-the-art software [ 31- 33] for pre-processing and alignment of data sets in combination with multivariate statistical analysis and advanced identification technology.
The "-k 1 --best" and "-m 1" modes of alignment reporting were also used in combination with the end-to-end k-difference (−v) alignment mode.
Zhou & Zhou used sequence profiles obtained not from CPD, but from structural alignment of small protein fragments, in combination with traditional sequence profiles.
In the presence of knee malalignment and anterior cruciate ligament insufficiency, correction of the leg alignment should be considered, possibly in combination with an anterior cruciate ligament reconstruction.
