Rearfoot and forefoot alignment evaluations were performed as described by Gross et al., and the ICC for intrarater reliability was 0.91 for the forefoot and 0.87 for the rearfoot [26].
Coordinate files of CATH domains for alignment quality evaluation were generated from corresponding PDB files using makedomains.perl (ver. 1.1) developed by Dr Martin (http://www.bioinf.org.uk/faqs/cath/).uk/faqs/cath/
This evaluation was also used to evaluate FT alignments versus spectral comparison in [42].
On simulated data, we know the correct chromosomal coordinates from the alignment and the evaluation is straightforward.
Evaluation was not speeded.
Since we do not know the ground truth for these alignments, only indirect evaluation is possible.
A potential method for performing such evaluation is inter-alignment agreement, as in indexing [ 8].
Results from this evaluation are shown in Figure 4, and individual alignments are included in the supplementary website.
The evaluation is enormous.
Evaluation is in progress.
The patellar alignment evaluation for MRI in this study was performed with eFilm Workstation (version 2.0.0) software.
