The phrase "alignment difficulties" is correct and usable in written English.
It can be used to describe challenges or issues related to achieving alignment in various contexts, such as teamwork, project management, or personal goals.
Example: "The team faced alignment difficulties that hindered their ability to meet the project deadline."
Alternatives: "coordination challenges" or "synchronization issues."
All proteins were aligned using CLUSTALX [ 79], and gene models refined to fix apparent alignment difficulties.
In contrast, the proposed feeding architecture is very easy to fabricate and it overcomes the alignment difficulties arising from the proximity and aperture coupled feeding structures.
Adding mirrors indeed increased the signals attenuation but induced critical alignment difficulties.
Moreover, the coating saved us the severe alignment difficulties that were a problem in PDE based conventional etalon modulators.
A second major reason for alignment difficulties is the diversity of methylation patterns at cytosine loci.
Introns were present in all of them, but these posed no particular alignment difficulties.
Contestants are judged on strength, flexibility, alignment, difficulty of the optional poses and overall execution.
Also briefly discussed are some significant areas of alignment difficulty found during the study.
So it's no surprise that a recent training survey by Mind The Product found that product managers' biggest challenges by far were around "stakeholder communication," "problems with alignment," "difficulty getting buy-in from higher-ups," and "keeping all the teams on the page". The real surprise in that survey?
We evaluate the different variant states separately in order to obtain accuracy measures for each type of event, as they differ in the degree of alignment difficulty.
In addition to these families, eight families had to be left out of the analysis because of short sequence length, high conservation and therefore uninformative alignments or difficulties to generate reasonable alignments due to varying numbers of repeated domains.
