The phrase "alignment at least" is not correct and lacks clarity in written English.
It may be intended to express a minimum standard for alignment, but it needs additional context to be fully understood.
Example: "We need to ensure that there is alignment at least among the key stakeholders before proceeding."
Alternatives: "minimum alignment" or "at a minimum, alignment".
This summer, the sport and the company were in rare alignment, at least in one sense: for the first time since it trademarked "Polo" in 1967, Ralph Lauren sponsored a polo team in the United States.
It is likely that the removal of gapped positions in the alignment at least partially contributes to the observed lack of clustering in the histamine receptor family, in particular as the histamine H1 receptor crystal structure was also used to select the binding site residues (see Methods).
Above, the four-substrate problem is discussed to indicate the importance of an atomistic analysis of cognate base pair alignment, at least in part, in order to begin to understand how noncognate NTPs are rejected.
Our observations on alignment and topological comparison measures are important for future multiple analysis studies as far as they indicate that the shape of the tree cannot always be predicted from the descriptive characteristics of the alignment, at least in the case where highly divergent sequences are considered.
Only merged alignments at least 5,000 nt long were used in the further analysis.
We selected a subset of alignments at least 100 bp long, and including at least 6 of 7 of our target species.
Compared with the 454 contigs, we found many more small insertions or deletions in the Illumina contigs, which could explain the worse alignments at least partly.
At the gaps in the alignments, at least 10% of the members (or at least 2) had to have non-gap characters in the gap position to be included in the diversity calculation of the alignment.
To avoid any bias from unsuccessful alignments, sequence pairs for which neither method yielded an alignment with at least one correct symbol alignment were excluded.
To measure correctness, we compute Smod, the ratio of the number of correctly aligned positions to the number of aligned columns in the evaluated alignment where at least one of each two aligned columns is present in the reference alignment.
For each pairwise LCB in the true alignment, we record a TP LCB prediction when the predicted alignment contains at least one correctly aligned nucleotide pair in that LCB.
