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The observations within each column of the alignment are assumed to evolve according to a phylogenetic tree t.
Thus, for large genomes, we may assume that adjacencies are independent (if rearrangements happen randomly), just as columns of an alignment are assumed to be independent in BC.
We consider an alignment of several sequences; all positions in this alignment are assumed to be independent, and thus may be modelled independently.
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In this way, particular textual personae will be construed according to the extent that the writer does assume such 'solidarity' with readers, and according to the particular value positions (via particular attitudinal assessments) of specific targets, and for which such writer-reader alignment is assumed.
An alignment is assumed to be optimal if it maximizes the alignment potential.
Rate heterogeneity at different positions in the alignment was assumed and modelled using a gamma distribution consisting of 8 categories [ 74].
The likelihood of each site is calculated given the particular ST and combined across the alignment or collection of alignments; in the latter case, all sites across all alignments are assumed to have evolved along precisely the same tree.
Polymorphisms can be distinguished from sequencing errors in post hoc analysis of the multiple-read alignments (McKenna et al. 2010) when the read alignments are assumed to be correct.
For alignment, languages are assumed to be independent except through their shared descent from the ancestor.
Sequence alignment approaches may be broadly divided into global alignment methods, where sequences are assumed to be homologous and alignable over their entire lengths, and local alignment methods, where only part of each sequence is assumed to be homologous and alignable (Durbin et al., 1998; Gusfield, 1997).
Thus we can claim that CMAPi is optimal for pairwise alignment provided that the residues are assumed to be ordered sequentially.
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CEO of Professional Science Editing for Scientists @ prosciediting.com