Sentence examples for alignment and then from inspiring English sources
That is, HHpred first searches through the template database using local alignment and then re-aligns a target to the top templates using global alignment.
PAGAN can reconstruct ancestral sequences for an existing alignment and then extend that by aligning new sequences against the extant or inferred ancestral sequences.
To solve the problem, we transform each original feature vector into a 2-dimensional feature matrix by means of kernel alignment, and then propose a novel kernel-aligned multi-view canonical correlation analysis (KAMCCA) method on the basis of the feature matrices.
Then, following the same procedure as step (b), VERSE runs ICORN to iteratively align reads to these pseudo-chromosomes, call SNPs and indels from read alignment, and then correct the reference with the called SNPs and indels.
Briefly, data was processed with background removal, calibration to an internal reference standard, alignment and then merging of scans.
The high ranked linear and conformational B-cell epitopes derived from several online web-servers (e.g., ElliPro, BepiPred v1.0, BcePred, ABCpred, SVMTrip, IEDB algorithms, SEPPA v2.0 and Discotope v2.0) were utilized for multiple sequence alignment and then for engineering the vaccine construct.
One may envision a strategy in which SV breakpoints are approximately localized (e.g. by analysis of local alignments) and then precisely identified using AGE to align only subsequences that flank SVs.
First, we generate optimal pairwise interface alignments and then use a version of the neighbor-joining algorithm to align multiple interfaces.
We removed all exonic sequences from the alignments and then randomized non-gapped columns in each alignment.
We applied these three programs to the list of matches obtained in the genome self-alignments, and then applied procedures for discarding segmental duplications (see Methods).
First, it finds collinear (synteny) blocks between the two genomes by creating pair-wise alignments and then it generates a global alignment for the entire region that covers the collinear blocks.
