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By either correction method, we can substantially attenuate the reference alignment bias, showing that RNA-Seq data aligned with standard methods requires a much larger allelic ratio for confidently predicting AEI.
Of those, UDPS sequence reads that can be aligned with standard sequence were 35,311 in average per sample, accounting for 94% of total reads), and the average read length was 350 bp per each sample).
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"We're trying to move closer to making sure that these decisions are aligned with standards," she said.
Such sequences are difficult to align with standard scoring schemes, because it is not clear which copies from the two organisms are orthologous.
Our work is aligned with the standard suggested by the regulatory agencies and allows to propagate uncertainty from hydrogeological, toxicological and behavioral parameters to the final health risk endpoint.
The ACMG recommendations on incidental findings in clinical sequencing are the first by any professional organization to acknowledge that genomic analysis should be aligned with the standard practice of medicine and point the way to an exciting future in which genomic information will begin to fulfill its lifesaving potential.
Each individual functional data-set was aligned with the standard stereotactic reference space, so that a group analysis based on the contrast-images could be performed.
Twelve healthy subjects participated in the sham control (mean age ± SD, 22.1±2.56) and were positioned in the Brainsight apparatus with their surface skull anatomy aligned with a standard MRI.
All the pathology laboratories used HbA1c assay methods aligned with the standard set by the Diabetes Control and Complications Trial 40 and undertook quality assurance for HbA1c assays.
The conversion of a regular sequence to a graph is trivial (Supplementary Fig. S1a) and two such graphs could be aligned with a standard dynamic-programming algorithm.
Tighten the screw in the opposite end of your stock into the drill motor's chuck, positioning the vise so it is aligned with the standard and spaced so that the stock is supported and will turn freely.
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