The phrase "alienation and despair" is correct and usable in written English.
It can be used to describe feelings of isolation and hopelessness, often in contexts related to mental health, social issues, or literature.
Example: "The protagonist's journey through the novel is marked by a profound sense of alienation and despair as they struggle to connect with those around them."
Alternatives: "isolation and hopelessness" or "estrangement and despondency".
They cannot address the profound sense of alienation and despair driving some Palestinians – especially young people".
Mr. Tooker, who died on March 27, emerged with one of the best-known depictions of modern alienation and despair.
Disconnection causes social disengagement and despair — and the behavior that is the product of alienation and despair.
His work explores burnt-out lives, delineating alienation and despair in stammering dialogue punctured by mordant, improbable songs.
Howe wrote that "Herzog" was a novel "driven by an idea" — the idea that modern man can overcome alienation and despair.
It's going to be a battle against the sense of alienation and despair so many people feel about politics and how it's been done in the past".
Mr. Winterbottom's "Wonderland" unfolds over a November weekend in contemporary London, which it depicts as a locus of alienation, loneliness and despair.
Their devastating portraits of upwardly mobile, desperately unhappy Italians captured an alienation, rootlessness and despair that seemed to rise with every percentage point of gross domestic product during Italy's boom years in the 1950s and '60s, as the feudal resignation of the past evolved into aestheticized existential ennui.
The two singles released either side are arguably the finest of the band's entire career, the widdley-widdley soft-rock balladeering of Motorcycle Emptiness and Little Baby Nothing, a beloved-by-fans hymn to "culture, alienation, boredom and despair", yet neither set the charts alight, stalling at 17 and 29 respectively.
Once, I was sent to the guidance counselor's office for being Sharpie'd in phrases like, "Culture alienation boredom and despair" and "Dead End Doll".
Frank found that getting drunk and beating up '"scum" were powerful ways of shutting down his emotions and not feeling the pain of alienation, loneliness, and despair.
