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Evolutionary conservation of amino acid substitution was predicted by ConSurf web server [ 55] by using a Bayesian algorithm (conservation scores: 1 4 variable, 5-6 intermediand, and 7 9 conserved) [ 56, 57].
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The WeederH algorithm measures conservation based on the sequence conservation as well as the motif occurrence's positions relative to the TSS.
Similarly, the algorithm considers conservation throughout the potential miRNA matching region rather than only seed conservation.
The UVs were further classified as high risk or low risk based on five methods: allele frequency, Polyphen algorithm, sequence conservation, Grantham matrix scores, and a combination of the Grantham matrix score and sequence conservation.
(I.e., this is not a conventional DG algorithm for conservation laws).
The proposed advection algorithm satisfies conservation and boundedness of the liquid volume fraction irrespective of the underlying flux polyhedron geometry, which differs from contemporary unsplit VOF schemes that prescribe topologically complicated flux polyhedron geometries in efforts to satisfy conservation.
This paper presents an approach to developing a resource allocation algorithm for conservation investment that incorporates the ecological stability of ecoregions under climate change.
Additional file 2: Supplementary Note 1. Criteria for functional prediction algorithms and conservation scores.
Pressey & Nicholls' (1989 a, b ) publications initiated an expanding discussion on possibilities of site-selection algorithms and conservation efficiency.
Candidate driver mutations and functional germline mutations were called based on the results from seven functional prediction algorithms and three conservation score algorithms using ANNOVAR [ 13] and dbNSFP v2.0 [ 14] (Additional file 2).
In particular, [32] and [36] extend and analyze the MLMC algorithm for scalar conservation laws and for systems of conservation laws, respectively.
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