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We used a novel methodology to derive individualised alerting thresholds, and then reviewed medicine use data in the three preceding days to identify any 'events' for which patients took their standby medicines to treat an exacerbation.
We have previously described an automated real-time safety monitoring tool, Data Extraction and Longitudinal Trend Analysis (DELTA), that is able to perform larger numbers of concurrent prospective analyses using a variety of statistical methodologies and alerting thresholds [ 18].
Fixed alerting thresholds are based on the average experience of a cohort [ 15, 16].
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E-prescribing software that permits the clinician to set the desired alerting threshold has lower reports of over-riding alerts.
With automation, Stackdriver users can now set a number of policies for how to react when certain alert thresholds are met.
The result shows that the neutron flux and gamma dose at the location of VUV detector can be mitigated below 100 n cm−2 s−1 and 10 Gy, respectively, which are the alert thresholds for non-critical electronics in ITER.
The "Off Alert Periods" (OFAP) (alert thresholds not breached) included June 1st to 30th, July 5th to 16th and July 26th to August 31st.
Two alert thresholds were defined for Ile-de-France as 31°C (T max) and 21°C (T min), corresponding to an increased risk of mortality of 50%.
The heat wave period was defined by considering the days on which both alert thresholds (T° max and T° min) were breached in Ile-de-France.
We investigated four classes of algorithms for triggering alert thresholds.
Alert thresholds are defined by selecting a percentile of the prediction distribution, between 50% and 100%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com