Beaux's assistant had added a dose of aldehyde in a quantity never used before.
Another line of research focused on the possible role of CS-borne aldehydes (such as acroline or acetaldehyde) which are known to mediate the CS-inflicted damage in other systems, such as on plasma proteins (Reznick et al, 1992).
This has significant regulatory implications since the environmental toxicology of aldehydes has been previously considered on an individual chemical basis with focus on specific aldehydes (e.g., acrolein or crotonaldehyde) of a subgroup (e.g., α,β-unsaturated aldehydes).
High enzymatic activity of aldehyde dehydrogenase (ALDH) is one of CSC hallmarks11,12.
The enzyme is a member of the large aldehyde dehydrogenase family of enzymes, proteins that initiate or speed up chemical reactions, that can defang troublesome aldehydes.
His research focuses on the role of aldehyde dehydrogenases (ALDHs) and glutathione (GSH) in metabolism, cellular responses to environmental stress and disease.
His research focuses on the role of aldehyde dehydrogenases, cytochrome P-450s and glutathione in metabolism and disease (specifically, alcohol-induced tissue injury, diabetes, gout and cancer).
Finally, we focused on the electronic structure of aldehyde toxicants as revealed by the selected HSAB descriptors and demonstrated how this structure was related to corresponding toxic reactivities and molecular targets.
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells.
The intramolecular Michael reaction of aldehyde enolates generated by imidazolium carbenes was explored for the synthesis of cyclopentane aldehydes.
Almost forty per cent of East Asians have a variant, less efficient form of aldehyde dehydrogenase, another enzyme necessary for alcohol processing.
