Perhaps, but we also cannot rule out the possibility that I26A mutation allows limited in vivo interaction with one of 38 enzymesmes [ 13] not previously detected in prior, albeit very rigorous, studies of BRCA1 binding [ 7, 14] and that such interaction is sufficient for ubiquitination of some BRCA1 substrates.
Unlike Frege's adversaries, though, Curry, writing after the development of the discipline of metamathematics, is able to give a far more rigorous (albeit in his case somewhat eccentric) account of what a formal system is.
Overall, experience with such programs has consistently suggested mortality impact, albeit with less rigorous study designs.
A rigorous, albeit extreme, solution would be to retain only genes having one and only one copy in all the species under study (an approach particularly suited when complete genomes are available).
Fifth, expressing the future LTC financing burden as a proportion of GDP necessarily requires the projection of general economic growth (albeit based on rigorous statistical treatment of historical trends and implemented independently by the Government Economist).
Binyavanga Wainaina may be a cultural phenomenon but he sees the world through a playful lens -- albeit one spiked with a rigorous moral and intellectual power.
Unlike the U.S., where the results of near-annual standardized tests under the No Child Left Behind Act call the shots, the Finns have only one mandatory -- albeit lengthy, high-stakes and rigorous -- standardized test at the end of high school.
This was surely one of the riskiest shows ever attempted on mainstream TV – one that invited the audience to identify with a serial killer, albeit one who operates to a rigorous code of ethics, dispatching only villains lacking his own moral finesse.
It is possible that the messages of accurate data collection advocated by the MES project were disseminated to these sites and they began their own, less rigorous data collection processes, albeit later in the study.
Accurate thermodynamic and phase equilibrium calculations, albeit elaborate and computer-intensive, represent the more rigorous and reliable way of approaching this optimization problem.
