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This reaction is catalyzed by ALA synthase (ALAS).
Alas, alas!
Furthermore, the crystal structure analysis of ALAS from Rhodobacter capsulatus [ 23] suggests that a missense mutation at Arg170 destabilizes PLP binding, which might be partially restored with excess amounts of PLP.
Furthermore, inhibition of heme biogenesis in HepG2 cells with succinylacetone, a 5-aminolevulinate synthase (ALAS) inhibitor, led to increased p53.
Furthermore, we elucidated the crosstalk among the components of the cascades taking part in TPA-mediated ALAS repression.
But alas, prematurely, and alas, disastrously.
ALAS, poor Goethe.
No such luck, alas.
ALAS, poor Oskar Lafontaine.
No, alas.
Using paper diaries alas.
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