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Breast cancer was induced by "air pouch technique" with a single dose of 25 mg/kg of 7, 12 - dimethylbenz[a]anthracene (DMBA).
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Investigations were performed using carrageenan induced rat air pouch model.
Infiltration of the cells into the rat granuloma air pouch was also significantly inhibited by kaempferol.
To assess the anti-inflammatory effect of the extract, rat air pouch linings were examined histologically.
MX-68 (0.5 mg kg−1 week−1), as well as MTX, inhibited infiltration of leukocytes into the air pouch.
Inflammation was produced by adding carrageenan into a newly formed air pouch and prostaglandins produced.
In the rat air pouch model, oral dosing of CJ-13,610 and zileuton resulted in selective inhibition 5-LO Xactivity from pouch exudate and ex vivo rat whole blood with similar potency to in vitro assay.
They used subcutaneous air pouch rat model as well as knee joints of normal rabbits [70].
Among many animal models of inflammation (sponge implant, paw edema, peritoneal, pleurisy, and air pouch), the air pouch model has the advantage of not involving internal organs, which can be damaged or perforated during sampling [21].
typhimurium in 1 ml PBS were injected into the air pouch cavities.
The air pouch model of PMN chemotaxis was used as described previously [59].
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