Sentence examples for aims at specificity from inspiring English sources

We have also found that we can generally identify more AS events using Scripture as isoform reconstruction tool, compared to using Cufflinks, because Scripture aims at maximizing sensitivity, while Cufflinks aims at specificity.

This low recall rate may be due to the stringent threshold of Cufflinks, which aims at maximizing specificity.

For the transcriptome reconstruction tool, in addition to Cufflinks [ 15], which aims at maximizing specificity, we have also tested Scripture [ 16], a computational algorithm aiming at higher sensitivity.

There are multiple ways in which investigators have identified SREs using administrative claims, ranging from approaches that maximized sensitivity of SRE measures to methods that aimed at higher specificity for specific SRE subtypes [ 11– 19] (Fig.  1).

In constructing the filters we have therefore aim at high specificity at the expense of sensitivity.

This approach to select only lesions observed on MRI studies by all seven readers aimed at high specificity for comparison with the two clinical assessment methods where ACW pain was either present or absent.

Development of PKMT inhibitors aiming at both specificity and potency can be challenging because most PKMTs contain highly similar pockets for binding the SAM cofactor and less-structured regions for binding protein substrates.

Since interaction data for all these genomes are not available, in order to validate this approach, we aim at high specificity (low number of false positives), and low sensitivity (high number of false negatives).

In the sequel, we present our classification, which aims at highlighting design specificities of the approaches.

So far, studies aimed at elucidating integration specificity were largely based on genomic screening and molecular biology methods.

Our work provides resources for functional and evolutionary studies aiming at understanding host specificity of pathogenic bacteria, functional redundancy between T3Es and the driving forces shaping T3E repertoires.