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Ultimately, the aim of relative effectiveness assessment is "to compare healthcare interventions in practice in order to classify them according to their practical therapeutic value" [ 8].
The importance of these clinically relevant differences is illustrated by the emergence of relative effectiveness as an important issue in the post-authorization stage… Ultimately, the aim of relative effectiveness assessment is "to compare healthcare interventions in practice in order to classify them according to their practical therapeutic value" [ 9].
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Cyclo-oxygenase-2 (COX-2) selective inhibitors have been associated with an increased risk of thrombotic cardiovascular events in placebo-controlled trials, but no clinical trial has been reported with the primary aim of assessing relative cardiovascular risk of these drugs compared with traditional non-steroidal anti-inflammatory drugs (NSAIDs).
Bi-variate and multivariate techniques will be used to assess the secondary aims of the relative independent effects of variables on the outcomes measures.
This finding has important implications for studies aiming the comparison of relative brain volumes of CKCSs with MCs [ 2, 4, 8], because large MCs have lower hindbrain volumes than small MCs.
In the present work, the experimental protocols were designed with the aim of evaluating the relative importance that these factors have on biocompatibility evaluation of BMMs.
Response surface methodology (RS M involving central composite design (CCD) was employed to optimize the sintering process for the preparation of magnesia partially stabilized zirconia (MgO-PSZ) with the aim of improving the relative density and bending strength of the materials.
Then, the developed model was used to simulate the co-transport of viruses and colloids in porous media under unsaturated conditions, with the aim of understanding the relative importance of various processes on the co-transport of viruses and colloids in unsaturated porous media.
The structural and optical properties of CdSe/ZnS core/shell nanocrystals are studied using a combination of valence force field and sp3s⁎ empirical tight-binding model with the aim of studying the relative impacts of ratios between core and shell radius in the fixed volume.
In our experimental set-up, the flow was driven by combined impinging jet and density perturbations forcing with the aim of determining their relative influence on the overall microburst behavior and, in particular, the initiation and structural evolution of the resulting vortex.
We present a comprehensive analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression in mCRC patients treated with cetuximab or panitumumab, with the aim of clarifying the relative contribution of these molecular alterations to resistance.
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