Not surprisingly, complete resection (R0 operation), which should be the aim of induction chemoradiotherapy, is associated with a better prognosis.
The aim of induction of labour is to reduce the rate of severe complications of hypertensive disease, such as postpartum hemorrhage, sever hypertension (diastolic BP ≥ 110 mmHg), eclampsia and HELLP syndrome.
Administration of DMARDs and oral steroids was at the rheumatologists' discretion, but intensive treatment with ADA + MTX was initiated with an aim of remission induction in those patients whenever appropriate.
The aim of the induction phase was re-establishing the expression of genes, such as Apaf-1, that have been shown to be silenced by HDAC-involving mechanisms, and that are linked to response to chemotherapy (Soengas et al, 2001).
In high-risk patients, cytotoxic drugs are used in two different phases of treatment: first, during induction CT, which is aimed at metastasis control and primary tumour resection; and second, during myeloablative chemotherapy (or high-dose CT) in association with stem-cell transplantation with the aim of consolidating induction CT and surgery [ 3].
Know the aim of the induction process.
Experiments were designed to investigate a new concept aiming for induction of graft-vs-malignancy (GVM) effect prior to stem cell transplantation (SCT).
Further studies were designed with the aim of evaluating the induction of genotoxic and carcinogenic effects in Swiss albino mice exposed to smoke and/or light since birth.
In the 21st century, an array of microbiological and molecular allow antigens for new vaccines to be specifically identified, designed, produced and delivered with the aim of optimising the induction of a protective immune response against a well-defined immunogen.
New, efficient mucosal adjuvants for human use have been designed based on, amongst others, bacterial toxins and their derivatives, CpG-containing DNA, and different cytokines and chemokines, with the aim of improving the induction of mucosal Th1 and Th2 responses.
Therefore we aim to further investigate specificity of induction of these genes by microbial infection in follow up studies.
