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As angiogenesis is a rare event in the healthy adult (Carmeliet, 2003; Folkman, 2006), mainly confined to the female reproductive cycle, therapeutic strategies have been devised that aim at inhibiting the formation of new tumour blood vessels (inhibition of angiogenesis) or at destroying the pre-formed tumour neovasculature (vascular targeting).
Various means are currently available to prevent and treat osteoporosis, most of which mainly aim at inhibiting the excess of bone resorption.
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Investigation of further targeted therapy approaches e.g. inhibition of signaling pathways is aiming at inhibiting other dysregulated tyrosine kinases or transcription factors.
Flurizan was aimed at inhibiting the formation of amyloid beta 42, which is a small protein called a peptide.
Both the Trump administration and a series of Danish governments have aimed at inhibiting Muslim migration without saying so explicitly within the regulations themselves.
These obligations, aimed at inhibiting illegal sharing of copyrighted material and created by the 2010 Digital Economy Act, include sending warning letters to those suspected of illegal sharing, as well as logging the activities of repeat offenders.
"A possible explanation for such behavior is that the former want to diffuse what is neglected by mainstream thinking, whereas the latter aims at inhibiting the diffusion of conspiracy news," say Bessi and co.
In this study, we investigated eight different culturing setups aiming at inhibiting biomass formation of Escherichia coli, based on nutrient limitations or the addition of growth inhibitors.
We have synthesised a novel series of compounds based on a 2-naphthamide pharmacore aimed at inhibiting the efflux pumps from Gram-negative bacteria.
Peptides derived from this EGFcyt loop structure may aid in the design of novel peptide therapeutics aimed at inhibiting growth of cancer cells.
Consequently, therapeutic intervention aimed at inhibiting the VEGFR-2 pathway has become a mainstay of treatment in cancer and retinal diseases.
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CEO of Professional Science Editing for Scientists @ prosciediting.com