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We think that our PF method would give useful and interesting results to physiologists that aim at inferring the brain's activation rules from neurons' activities.
Recently, integrated methods aim at inferring modules as densely connected regions in interaction networks that is regions which are not only connected but also contain a high amount of edges, certainly inspired by the successes of approaches based on network data alone which made use of this idea.
Two general approaches have been proposed for that purpose: (i) consensus methods that aim at inferring a unique mean structure representative of the data and (ii) ensemble methods that yield a population of structures.
52 Here, we do not attempt to review that very active field comprehensively, but instead focus on studies that explicitly aim at inferring the DFE from this type of empirical data.
Put differently, this implies that C3NET does not aim at inferring the entire network underlying gene regulation, instead, it aims at its core structure and, hence, it is more conservative than all other methods.
Second, while phylogenetic trees usually aim at inferring the relationships between homologous sequences and their hypothetical ancestors, sequence similarity networks instead display significant resemblances between any sequences (in gene and protein networks) or any entities (in genome or sample networks), in a topologically less constrained, and in practice much more inclusive, framework.
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The third inverse step, which exploits cross-borehole flowmeter tests, is aimed at inferring inter-borehole fracture connectivity and transmissivities.
We review here different SELEX-based methods, with particular emphasis on the experimental design and on the applications aimed at inferring protein DNA interactions.
Finally, we performed a third mode of assessment aimed at inferring student perceptions regarding evolution.
However, there is one study aimed at inferring tumor primary site from point mutations [ 11].
More detailed analyses aimed at inferring demographic parameters for this data set will be submitted as an independent manuscript elsewhere.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com