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Furthermore, we suggest how systems biology can help in the next generation mAb glycoengineering process by aiding in data analysis and guiding engineering efforts to tailor mAb glycan and ultimately drug efficacy, safety and affordability.
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Optional statistical filters have been included to aid in data analysis.
GMC aided in data analysis and in revising the manuscript.
PT aided in data analysis and critically reviewed the manuscript.
JM, AL, CV, SW and PD aided in data analysis and interpretation of data.
EPD and VK participated in the design of the study and aided in data analysis.
GH, LB, CE, DA, and CMG aided in data analysis and manuscript preparation.
GP conceptualized the Fitness Assay, supervised and aided in data analysis.
JH provided guidance over the entire project, and aided in data analysis and editing of the manuscript.
HW performed the Phylogenetic tree construction with Minimum Evolution and Maximum Parsimony methods and aided in data analysis.
CH conceived the study hypothesis, participated in data and study analysis and interpretation; MR aided in data analysis; BL established the VDIS study, performed data analysis and participated in study analysis and interpretation.
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