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Many cellular components (macrophages, dendritic cells, neutrophils, T-cells, and B-cells), cell surface molecules, signaling components, and humoral components interact and aid the progression of RA [ 19].
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Considering that several iridovirus agents can induce apoptosis during infection, and that virally induced apoptosis aids the progression of replication and dissemination [ 44, 45], these apoptosis-regulating genes might manipulate the balance of life and death in STIV infected cells.
Monocytes, an important subset of the myeloid arm of the immune effectors are known to be the major inducers of resistance in tumor cells and are shown to significantly aid in the progression of cancer in tumor-bearing hosts [23], [24], [25].
Recent studies have shown that TEADs and their coactivators aid in the progression of various cancers, including the difficult to treat glioblastoma, liver and ovarian cancers.
It is now well established that loss of E-cadherin and up-regulation of mesenchymal markers result in subsequent activation of signal transduction events such as Wnt/β-catenin pathway that aid to the progression of metastasis [ 7].
Cancer cells use the Hsp90 chaperone machinery to protect mutated or overexpressed oncoproteins, which aids in the progression of cancer.
Vgll3 also potentially plays a role in cancers, it aids in the progression of soft-tissue sarcoma and also in the development of myxoinflammatory fibroblastic sarcoma., However, in ovarian cancers Vgll3 could possibly play a tumor suppressor role.
Cross-validation algorithms aid in determining the progression of accuracy of the key classification model and are typically taken from the input data set.
The increase of ColX levels in serum possibly serve as a marker of local chondrocyte hypertrophy and differentiation, and may even aid in describing the progression of OA disease.
However, no direct association has been shown between the presence of microchimeric cells and the progression of AID.
Future studies investigating the effects of HA and hylans on cartilage in well-controlled clinical studies may help determine whether intra-articular HA and hylans aid in chondroprotection and slowing the progression of disease, and whether the MW of the HA formulation contributes to its efficacy.
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