Sentence examples for aid functioning from inspiring English sources
Most human cells express up to nine active DNA cytosine deaminases, with one family member (AID) functioning in antibody gene diversification and most family members protecting against virus and transposon replication [ 6].
Importantly, the characterisation of gene products with previously unknown functional properties through community detection has the potential to aid function assignment.
Legal Aid functions like a public defenders office, the government agency that represents the poor in most other big cities.
This salience of wealth suggests that student aid has an important role to play, since for disadvantaged students, aid functions like financial equity in easing stress at home and blunting hard tradeoffs (between work and school, for instance).
Therefore AID function is expected to be tightly regulated to prevent the generation of DNA lesions.
Therefore, AID function, while crucial to the development of an efficient immune response, can pose a risk to DNA stability in B cells.
The frequency of these events in wild type B cells is extremely low (below one translocation every ten million cells), but it is increased in the absence of p53, p19ARF or ATM, reflecting that DNA damage and oncogenic stress pathways are activated downstream of AID function to prevent aberrant joinings or spreading of cells that harbour lymphomagenic translocations.
The impact of AID function in B cell neoplasia development has been addressed in a number of in vivo models, including IL6 [21], [21] and pristane [23] promoted plasmacytomas, BCL-6-induced diffuse large B cell lymphoma [22], Eμ-Myc model of B cell lymphoma [24] and a myc-induced multiple myeloma model [25].
Just how AID functions to regulate the central checkpoint in the BM is unclear.
AID function is critical and dsDNA breaks occur as in CSR.
Quality control is a potential problem for OTC hearing aid purchasers since salespeople may not have sufficient knowledge to check hearing aid function prior to sale.
