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Discover LudwigThe phrase "aid activity" is correct and usable in written English.
It can be used to refer to actions or initiatives that provide assistance or support, often in a humanitarian or developmental context.
Example: "The organization is focused on promoting aid activity in underprivileged communities to improve their living conditions."
Alternatives: "assistance efforts" or "support initiatives."
Exact(60)
In addition, it is possible that the cell-cycle regulation of AID activity and AID's specific requirement for transcription limit the impact of this molecule in meiotic recombination.
Histone monoubiquitination may occur in response to AID activity, but could also be a signal for AID recruitment because AID colocalized with mUb-H2B as visualized by immunofluorescence microscopy (Fig. 5).
Although these data point to a likely role of AID in disease pathogenesis in CLL, the evidence for in vivo AID activity is scarce: typical AID off-target damage, such as somatic mutations of the BCL6 gene [41] or c-myc/IgH translocations [42] are very rare events in CLL and IgVH genes in AID-expressing CLL cells are frequently unmutated.
One of the best-characterized requirements for AID activity is that the target sequence be transcriptionally active (Chaudhuri et al, 2003; Ramiro et al, 2003; Pavri & Nussenzweig, 2011).
The described decrease in AID activity on the methylated substrate could be regarded as an argument against AID's involvement in demethylation pathways37.
In addition, studies of activated B-cells, which provide the natural environment for the AID activity, do not explain how the genomes of breast cells become edited by the APOBEC proteins.
Why nonimmunoglobulin loci are susceptible to AID activity is unknown.
But significant, coordinated aid activity is going on inside the city this winter.
For instance, structural determinants of AID activity on different substrates remain to be identified.
In order to overcome these difficulties, there needs to be a clear separation between military and humanitarian aid activity.
These findings suggest that RPA stabilizes the single-stranded DNA produced during transcription, to enhance AID activity.
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