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"To live in freedom," De Tocqueville warned, "one must grow used to a life full of agitation, change and danger".
In the absence of any sort of public agitation, change will come from the top down, not from the bottom up.
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The well-described triad of symptoms seen in serotonin syndrome consists of changes in mental status, like confusion or agitation; changes in heart rate, blood pressure or body temperature; and changes in muscle function, usually tremors or exaggerated reflexes.
In contrast, patients whose state of agitation changed significantly following medications given at admission would show lower correlation values with both scales.
Therefore, when excluding items that are related to Parkinson's disease symptomatology and treatment side effects (i.e. lack of energy, agitation, sleep changes, irritability appetite changes, concentration problems, and fatigue), no significant difference between patients and controls was observed (Patients: mean 2.8; Controls: mean 1.2, P = 0.242).
Wind the clock back far enough in relation to any issue and you find that the original agitation for change came from activists, NGOs and other organs of civil society.
The announcement follows agitation for change led by the billionaire investor Nelson Peltz, who last year won three seats on an expanded Wendy's board as he pushed for steps to reward shareholders.
Mitchel became an editor of The Nation in 1845, but over the next three years he grew increasingly disillusioned with the idea of legal and constitutional agitation for change in Ireland.
We report a homozygous MAPT R406W mutation carrier who developed agitation, personality change and increased rigidity during his early thirties, followed by memory impairment, delusions, obsessive rituals and social disinhibition, leading to a diagnosis of bvFTD.
The agitation slowly changed into a general anti-Congress organisation.
Similar agitations for change have historically resulted in ill-fated movements in recent decades.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com