Sentence examples for aging modified from inspiring English sources

As protein clearance mechanisms become impaired upon aging, modified proteins normally targeted for degradation by post-translational modification, such as phosphorylation and acetylation, may accumulate and take on toxic functions.

In this view, rather than GCs promoting brain aging, aging modifies GC signaling, and the resulting altered functions of GC regulatory pathways generate much of the brain aging phenotype.

This information may provide a foundation for further mechanistic studies investigating how aging modifies alloimmunity, as well as translational studies that investigate how older people respond differently to solid organ allografts.

For example, aging modifies the structure-function relationship of the genome through accumulation of mutations, changing epigenetic profiles (both changes in DNA methylation patterns and histone modification) and altered telomere dynamics [ 5, 6].

To investigate the association of the levels of methylglyoxal-derived hydroimidazolone AGE modified proteins (MG-H1-AGE) with cardiovascular disease (CVD) mortality in an 18-year follow-up study in Finnish nondiabetic and diabetic subjects.

Bronze Age modified cranial vaults from El Mirador Cave (Sierra de Atapuerca, Spain) are also consistent with skull-cups, although the authors excluded any symbolic behavior associated with the processing and consumption of the bodies [13].

Age modified the relative effect (p = 0.018).

Age modified the association between vaccination status and symptom severity in patients who were influenza positive.

Parasite density, ID, inflammation, and age modified the effects of parasitaemia on hepcidin (Figs. 2F, 4).

We did not find evidence that age modified OCPs' associations with growth (data not shown).

In sensitivity analyses, we examined separately whether sex and age modified the relationship between sleep and diabetes.