Exact(3)
Although estrogen administration has been shown to have positive effects on skin by delaying or preventing skin aging manifestations (Brincat 2000; Sator et al 2004), understanding the effects of estrogen on skin is complicated by a number of factors.
Estrogen administration has positive effects on human skin by delaying or preventing skin aging manifestations, but the use of estrogen replacement is a risk factor in breast and uterine cancer.
Conversely, there may be SERMs currently in use or in development that may act as estrogen agonists in human skin and the hair follicle and may potentially provide a useful therapy for clinical application to delay the aging manifestations of the skin.
Similar(57)
In Caucasians, for example, two extrinsic skin aging manifestation forms are divided regarding their skin type.
Furthermore, it is important to investigate the extrinsic skin aging in different populations as environmental exposure lead to ethnic-specific skin aging manifestation.
Recently, an epidemiological study comparing the skin aging manifestation in Caucasian women from Düsseldorf in Germany with Japanese women from Nagoya in Japan discovered further underlying reasons for the ethnic-specific manifestation in these two populations.
Caucasians have an earlier onset and greater skin wrinkling than other populations and in general increased pigmentary problems are seen in Asians and in African-Americans.,, One main influencing factor for the ethnic-specific skin aging manifestation is the genetically determined skin type as there is an ethnic variation in melanin content and composition.
In other words, diseases of aging are manifestations of biological aging.
Aging and its manifestations such as age-related diseases appear with excessive growth-promoting signaling, when actual growth is not longer possible.
According to the hyperfunction theory, aging and its manifestations are never programmed: even menopause and the death of Pacific Salmon are not programmed.
11 Elderly patients may be at higher risk for the HP-negative, NSAID-negative ulcers as reduction in gastric or duodenal mucosal barriers often occurs with aging. 1 Manifestations of PUD in elderly patients may be atypical.
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