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As mentioned above, the synthesis of epidermal HA is influenced by the underlying dermis and is under separate controls from the synthesis of dermal HA., Progressive reduction of the size of the HA polymers in skin as a result of aging has also been reported.
However, aging has also been found to increase the inequality before retirement.
Immune senescence with aging has also played a crucial role in AD pathogenesis and influences the effect of anti-Aβ immunotherapy.
With today's prolonged human lifespan, aging has also been considered as an obesogenic factor given the increased visceral fat associated with aging [4].
Aging has also been associated with both a disruption of mitochondrial function [3] along with the steady increase in ROS species, a state that may seem paradoxical as the mitochondria may be the prime source of the ROS.
Aging has also been demonstrated to have detrimental effects upon tactile sensory tasks.
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The demographics of aging have also played a role, because the generations that lived through the nation's glory years have clung to their faxes.
As with evolutionary geneticists, molecular biologists working on aging have also focused on demographic traits.
Previous studies on cast aging have also reported rapid exhaustion of most of the ammonium present in the castings [8, 55, 56].
DNA methylation (DNAm) changes associated with cancer and aging have also been observed in peripheral blood samples from postmenopausal women [15], [16].
Several miRNAs differentially expressed with aging have also been identified.
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